21+ only. Alexis 420 is for adults 21 and older. By browsing you confirm you're of age.
5 licensed dispensaries in Sioux Falls, closest deals, hours and who's open now. Every spot is on South Dakota's state license list.
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Alexis 420 lists 5 licensed dispensaries in Sioux Falls, SD: Canna-Care, East River Farms, Genesis Farms, Royzzz, The Flower Shop. Every one is on South Dakota Department of Health, Medical Cannabis Program's license list.
Yes. South Dakota allows medical cannabis only, so every dispensary in Sioux Falls, SD needs your state medical card and a photo ID.
Open past 10 PM at least one night: East River Farms.
Every store here is on South Dakota Department of Health, Medical Cannabis Program's license list, last checked Oct 14, 2026. See the state list ↗
21+ only. Alexis 420 is for adults 21 and older. By browsing you confirm you're of age.