Claim your listing
South Dakota · 55 spots · 28 cities

Dispensaries in
South Dakota

South Dakota allows medical cannabis only, so you need a state medical card to shop. Here's every licensed dispensary in the state, city by city.

55licensed dispensaries
28cities and towns
Medicalcard required at every store
Oct 14last checked against the state list
Pick a city

Where in
South Dakota?

Biggest scenes first. Every city links to its full list with a map, hours and what's open now.

Rapid City5 spotsSioux Falls5 spotsYankton5 spotsAberdeen4 spotsNorth Sioux City4 spotsHuron3 spotsMitchell3 spotsWatertown3 spotsBrookings2 spotsFort Pierre2 spotsSturgis2 spotsBelle Fourche1 spotBig Stone City1 spotBox Elder1 spotBrandon1 spotChamberlain1 spotColome1 spotCuster1 spotDeadwood1 spotHarrisburg1 spotHartford1 spotHot Springs1 spotLake Andes1 spotPierre1 spot
Every city, A to Z
Aberdeen 4Belle Fourche 1Big Stone City 1Box Elder 1Brandon 1Brookings 2Chamberlain 1Colome 1Custer 1Deadwood 1Fort Pierre 2Harrisburg 1Hartford 1Hot Springs 1Huron 3Lake Andes 1Mitchell 3North Sioux City 4Pierre 1Rapid City 5Sioux Falls 5Spearfish 1Sturgis 2Tea 1Vermillion 1Wagner 1Watertown 3Yankton 5

Questions

How many dispensaries are in South Dakota?

Alexis 420 lists 55 licensed dispensaries in South Dakota across 28 cities and towns, checked against South Dakota Department of Health, Medical Cannabis Program on Oct 14, 2026.

Which cities in South Dakota have the most dispensaries?

Rapid City (5), Sioux Falls (5), Yankton (5).

Do I need a medical card in South Dakota?

Yes. Every dispensary in the state is medical-only.

How do I know a dispensary in South Dakota is licensed?

Every store on Alexis 420 comes from South Dakota Department of Health, Medical Cannabis Program's own license list. Each store page shows its license and links to the state record.

Source: South Dakota Department of Health, Medical Cannabis Program. See the state list ↗

21+ only. Alexis 420 is for adults 21 and older. By browsing you confirm you're of age.