Adult-use + Medical21+ with ID, or your medical card
Open lateMondays till 12 AM
MO license DIS000036Adult-use + Medical · Active · checked Oct 14, 2026See the state record ↗
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About Root 66 Dispensary
Root 66 Dispensary is a licensed adult-use and medical dispensary at 6660 Manchester Ave in St. Louis, MO. The owner hasn't added a description yet.
Hours
MondayLATE
8 AM to 12 AM
TuesdayLATE
8 AM to 12 AM
WednesdayLATE
8 AM to 12 AM
ThursdayLATE
8 AM to 12 AM
FridayLATE
8 AM to 12 AM
SaturdayLATE
8 AM to 12 AM
SundayLATE
8 AM to 12 AM
Hours from the store's map listing, checked Oct 14, 2026. Not confirmed by the owner yet.
Questions
Is Root 66 Dispensary a licensed dispensary?
Yes. Root 66 Dispensary holds Missouri adult-use and medical license DIS000036. Alexis 420 last checked it against Missouri Department of Health and Senior Services, Division of Cannabis Regulation (DCR) on Oct 14, 2026.
Is Root 66 Dispensary adult-use or medical?
Both. Adults 21+ can shop with a valid photo ID, and medical patients can shop with their card.
What are Root 66 Dispensary's hours?
Monday 8 AM to 12 AM, Tuesday 8 AM to 12 AM, Wednesday 8 AM to 12 AM, Thursday 8 AM to 12 AM, Friday 8 AM to 12 AM, Saturday 8 AM to 12 AM, Sunday 8 AM to 12 AM. Hours can change on holidays, so call ahead if you're cutting it close.
Where is Root 66 Dispensary?
6660 Manchester Ave, St. Louis, MO 63139. Call (314) 517-4296 for directions.
